Manufacture of harmless combinations of sulfocyanic acid.



UNITED STATES JOSEPH NERKING, 0F DUSSELDORF, GilRMANYfASSIG-NOR T0CHEMISCHE FABRIK REISHOLZ, G. 'M. B. Ii, 0F DUSSELDORFREISHOLZ, GERMANY.

MANUFACTURE HARMLESS COMBINATIQNS OF SULFOCYANIC ACID.-

\ Specification of Letters Patent.

Patented Dec. 5, 1911.

No Drawing. Original application filed May 2, 1911, Serial N 6. 624,602.Divided and this application filed August 3, 1911. Serial No. 642,202.

To all whom it may concern:

Be it known that I, JosErH NERKING, a citizen of the Empire of Germany,residing at Dusseldorf, in the Empire of Germany, have invented a newand useful Manufacture of Harmless Combinations of Sulfocyanic Acid, ofwhich" the following is a specification.

This application is a division of an application filed by me May 2nd,1911, under Serial Number 624,602.

Salts of sulfocyanic acid (I-IONS), such as sulfocyanate of potassium,sulfocyanate of sodium, sulfocyanate of ammonium, have been employed asprophylactics against the decomposition of teeth and the mycodermitis,also as antispasmodics and sedatives, but they are objectionable onaccount of their poisonousness, for which reason they are nearly nolonger employed.

My invention relates to the manufacture of new combinations ofsulfocyanic acid, which are harmless and therefore suitable formedicinal purposes.

The invention essentially consists in the combination of salts ofsulfocyanic acid with albumen of any description, either alone or inconjunction with other substances.

When salts of sulfocyanic acid are mixed with albumen in the dry ormoist condition or with solvents, solid gummy bodies or solutions of thesame respectively will be formed, which bodies when dry are partlydifiicultly soluble in water or spirit or wine and partly insoluble. Thesoluble part of the bodies eoagulates on boiling the solution,

also on the addition of strongeracids,

While the insoluble part simply swells up in water. Both parts containmore or less sulfocyanic acid (HCNS) in proportion to the concentrationof the reacting solutions. Such combinations of the sulfocyanic acid maybe formed from animal albumens (ovalbumen, casein) as well as fromvegetable albumens, however, the casein and the vegetable albumensrequire to be first dissolved by the addition of an alkali or analkaline earth, such as for example. carbonate of sodium or hydrate oflime.

to add so much water or rather spirit of Wine as torender the mixingeasy. For larger quantities it is best to let the two components, viz.,the albumen and the salt of sulfocyanic acid, act upon each other in awatery solution, or the salt of sulfocyanic acid may be addedundissolved or in an alcoholic solution.

When to a concentrated solution of albumen a larger quantity ofundissolved salt of sulfocyanic acid is added, the whole mass willcoagulate and the sediment can be separated by pressing, washed out witha little spirit of wine and dried at 40 centigrade. This is for examplethe case, if the concentrated solution of albumen is made by dissolving2 kilograms of dry ovalbumen in 5 liters of water, and from 4 to 5kilograms of sulfocyanate of ammonium are added to the-solution. Thepreparation so obtained contains about 33% of HCNS and can be mixed withany quantity ofpowdered albumen so as to obtain any percentage of HCNSrequired by the physician. This method has been found to be the mostpreferable for large quantities and for preparations richest insulfocyanate of albumen.

It does not matter, whether sulfocyanate of ammonium or sulfocyanate ofpotassium or sulfocyanate of sodium or sulfocyanate of calcium orsulfocyanate of strontium or any other salt of sulfocyanic acid beemployed in the process, since in the combination with the albumen onlyis a considerable component.

I claim:

1. The method of manufacturin harm-' less combinations of sulfocyanicacid, wh ch consists in dissolving an albumen 1n a solvent, adding asalt of sulfocyanic acid,

allowing the mass to coagulate, separating ammonium, separating thesediment by pressing washing out the separated mass 10 with a littlespirit of wine, and drying the mass.

JOSEPH NERKING. [L. s.] Witnesses:

ALBERT F. NUFER, LOTTA LOSKMAN.

